Anti-coagulant, Unfractionated Heparin
Where is Heparin made?
19 companies sell it under their own name and 6 repackagers rebottle it. Their labels name 22 factories in the United States, India, China, Australia and Norway.
United States 11India 5China 4Australia 1Norway 1
Companies and their factories
| Company on the label | Factory | Where | Last FDA inspection |
|---|---|---|---|
| Fresenius Kabi, LLC Heparin Sodium200 [USP'U] per 100 mL, 1000 [USP'U] per 1 mL, 5000 [USP'U] per 0.5 mL, 5000 [USP'U] per 1 mL, 5000 [USP'U] per 100 mL, 10000 [USP'U] per 1 mL · NDC 63323-276, 63323-540, 63323-542 +12 | Fresenius Kabi USA, LLCMakes it and tests it | Grand Island, NY, United States | Problems found, fixed voluntarilyOct 2023 |
| Fresenius Kabi USA, LLCMakes it and tests it | Melrose Park, IL, United States | Problems found, fixed voluntarilyAug 2023 | |
| Fresenius Kabi USA, LLCMakes it and tests it | Wilson, NC, United States | Problems found, fixed voluntarilyFeb 2026 | |
| HP Halden Pharma ASMakes it, tests it and packages it | Halden, Norway | Problems found, fixed voluntarilyMay 2023 | |
| Hospira, Inc. Heparin Sodium and Dextrose, Heparin Sodium200 [USP'U] per 100 mL, 1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL, 5000 [USP'U] per 100 mL, 10000 [USP'U] per 1 mL, 10000 [USP'U] per 100 mL · NDC 0409-2720, 0409-2721, 0409-1316 +12 | Hospira, Inc.Makes it, tests it, packages it and labels it | Rocky Mount, NC, United States | No problems foundFeb 2025 |
| Hospira, Inc.Makes it, tests it, packages it and labels it | McPherson, KS, United States | Problems found, fixed voluntarilyJan 2025 | |
| Pfizer Healthcare India Private LimitedMakes it, tests it, packages it and labels it | Anakapalli, India | Problems found, fixed voluntarilyOct 2022 | |
| Pharmacia Hepar LLCMakes the active ingredient and tests it | Franklin, OH, United States | No problems foundMay 2024 | |
| Baxter Healthcare Corporation Heparin Sodium In Sodium Chloride200 [USP'U] per 100 mL · NDC 0338-0431, 0338-0433, 0338-0424 +1 | Baxter Healthcare CorporationMakes it, tests it, packages it, labels it and sterilizes it | Marion, NC, United States | Serious problems, FDA actionFeb 2024 |
| Baxter Healthcare CorporationMakes it, tests it, packages it, labels it and sterilizes it | Jayuya, PR, United States | Problems found, fixed voluntarilyJul 2024 | |
| Baxter Healthcare Pty LtdMakes it, tests it, packages it, labels it and sterilizes it | Old Toongabbie, Australia | Problems found, fixed voluntarilyJul 2022 | |
| Gland Pharma Limited1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL · NDC 68083-427, 68083-428, 68083-136 | Fosun Wanbang (Jiangsu) Pharmaceutical Group Co., Ltd.Makes it, tests it, packages it and labels it | Xuzhou, China | Problems found, fixed voluntarilySep 2023 |
| Gland Pharma LimitedMakes it, tests it, packages it and labels it | Hyderabad, India | Problems found, fixed voluntarilyJul 2024 | |
| Gland Pharma LimitedMakes it, tests it, packages it and labels it | Hyderabad, India | Problems found, fixed voluntarilyJun 2023 | |
| McKesson Packaging Services Business Unit of McKesson Corporation1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL, 20000 [USP'U] per 1 mL · NDC 63739-920, 63739-931, 63739-942 +6 | Eugia Pharma Specialities LimitedMakes it and tests it | Sangareddy, India | Serious problems, FDA actionFeb 2026 |
| Shenzhen Hepalink Pharmaceutical Group Co., Ltd.Makes the active ingredient | Shenzhen, China | Problems found, fixed voluntarilyJun 2025 | |
| Shenzhen Techdow Pharmaceutical Co., Ltd.Makes it and tests it | Shenzhen, China | Problems found, fixed voluntarilySep 2019 | |
| Northstar Rx LLC.1000 [USP'U] per 1 mL, 2000 [USP'U] per 2 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL, 20000 [USP'U] per 1 mL · NDC 72603-250, 72603-234, 72603-179 +8 | Nanjing King-Friend Biochemical Pharmaceutical Co., Ltd (API and FDF Site)Makes it | Nanjing, China | Problems found, fixed voluntarilyNov 2023 |
| Shenzhen Hepalink Pharmaceutical Group Co., Ltd.Makes the active ingredient | Shenzhen, China | Problems found, fixed voluntarilyJun 2025 | |
| Shenzhen Techdow Pharmaceutical Co., Ltd.Makes it and tests it | Shenzhen, China | Problems found, fixed voluntarilySep 2019 | |
| Fresenius Kabi USA, LLC Heparin Sodium1000 [USP'U] per 1 mL · NDC 65219-066 | Fresenius Kabi USA, LLCMakes it and tests it | Grand Island, NY, United States | Problems found, fixed voluntarilyOct 2023 |
| Fresenius Kabi USA, LLCMakes it and tests it | Melrose Park, IL, United States | Problems found, fixed voluntarilyAug 2023 | |
| Hepalink USA Inc.1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL, 20000 [USP'U] per 1 mL · NDC 81952-112, 81952-115, 81952-113 +3 | Shenzhen Hepalink Pharmaceutical Group Co., Ltd.Makes the active ingredient | Shenzhen, China | Problems found, fixed voluntarilyJun 2025 |
| Shenzhen Techdow Pharmaceutical Co., Ltd.Makes it and tests it | Shenzhen, China | Problems found, fixed voluntarilySep 2019 | |
| Pfizer Laboratories Div Pfizer Inc Heparin Sodium1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL · NDC 0069-0058, 0069-0043, 0069-0137 +2 | Pharmacia & Upjohn Company LLCMakes it, tests it, packages it and labels it | Kalamazoo, MI, United States | Problems found, fixed voluntarilyJun 2023 |
| Pharmacia Hepar LLCMakes the active ingredient and tests it | Franklin, OH, United States | No problems foundMay 2024 | |
| Sandoz Inc.1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL, 20000 [USP'U] per 1 mL · NDC 0781-3543, 0781-3540, 0781-3538 +6 | Shenzhen Hepalink Pharmaceutical Group Co., Ltd.Makes the active ingredient | Shenzhen, China | Problems found, fixed voluntarilyJun 2025 |
| Shenzhen Techdow Pharmaceutical Co., Ltd.Makes it and tests it | Shenzhen, China | Problems found, fixed voluntarilySep 2019 | |
| BE Pharmaceuticals Inc.2000 [USP'U] per 2 mL, 5000 [USP'U] per 0.5 mL · NDC 71839-117, 71839-118 | Be Biosol Private LimitedMakes it and tests it | Medchal-Malkajgiri, India | Problems found, fixed voluntarilyNov 2024 |
| Cantrell Drug Company0.5 [USP'U] per 1 mL, 1 [USP'U] per 1 mL, 2 [USP'U] per 1 mL, 4 [USP'U] per 1 mL, 5 [USP'U] per 1 mL, 10 [USP'U] per 1 mL · NDC 52533-148, 52533-100, 52533-104 +12 | Cantrell Drug CompanyMakes it and compounds it | Little Rock, Arkansas, United States | Problems found, fixed voluntarilyAug 2018 |
| Hikma Pharmaceuticals USA Inc. Heparin Sodium1000 [USP'U] per 1 mL, 5000 [USP'U] per 0.5 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL · NDC 0641-0391, 0641-2450, 0641-0410 +4 | Hikma Pharmaceuticals USA Inc.Makes it, tests it, packages it and labels it | Cherry Hill, NJ, United States | No problems foundMay 2026 |
| Meitheal Pharmaceuticals Inc.1000 [USP'U] per 1 mL, 2000 [USP'U] per 2 mL, 5000 [USP'U] per 0.5 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL, 20000 [USP'U] per 1 mL · NDC 71288-402, 71288-449, 71288-404 +7 | Nanjing King-Friend Biochemical Pharmaceutical Co., Ltd (API and FDF Site)Makes it | Nanjing, China | Problems found, fixed voluntarilyNov 2023 |
| Phlow Corp. Heparin Sodium1000 [USP'U] per 1 mL · NDC 81565-203 | Fresenius Kabi USA, LLCMakes it and tests it | Grand Island, NY, United States | Problems found, fixed voluntarilyOct 2023 |
| B. Braun Medical Inc. Heparin Sodium in Sodium Chloride200 [USP'U] per 100 mL, 5000 [USP'U] per 100 mL, 10000 [USP'U] per 100 mL · NDC 0264-3462, 0264-9872, 0264-3301 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Civica, Inc. Heparin Sodium1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL · NDC 72572-250, 72572-255 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Plano Pharmaceuticals Inc.5000 [USP'U] per 1 mL · NDC 87188-102 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Sagent Pharmaceuticals1000 [USP'U] per 1 mL, 5000 [USP'U] per 1 mL, 10000 [USP'U] per 1 mL, 20000 [USP'U] per 1 mL · NDC 25021-401, 25021-400, 25021-403 +2 | The label doesn't name the factory. Plants this company names for other drugs | ||
Repackaged by
These companies buy Heparin in bulk and rebottle it, often for mail-order, clinic or hospital pharmacies. If your bottle shows one of these names, open its NDC to see who made the pills inside.
- Cardinal Health 107, LLC:
55154-9583,55154-2380,55154-9589,55154-5130+3 - General Injectables & Vaccines, Inc.:
52584-540,52584-262 - HF Acquisition Co. LLC. DBA HealthFirst:
51662-1409,51662-1434,51662-1486,51662-1578+2 - Henry Schein, Inc.:
0404-9979,0404-9872 - Medical Purchasing Solutions, LLC.:
71872-7351,71872-7352,71872-7364,71872-7365 - Remedyrepack Inc.:
70518-4547
Recalls
- Oct 1, 2026 · Class II · Shenzhen Techdow Pharmaceutical Co., Ltd.
Lack of Assurance of Sterility - Aug 1, 2024 · Class I · Baxter Healthcare Corporation
Microbial Contamination of Sterile Products; out of limit results obtained for endotoxin testing. - Feb 28, 2023 · Class II · Sagent Pharmaceuticals Inc
Labeling: Not elsewhere classified - Dec 29, 2022 · Class II · Pfizer Inc.
Lack of assurance of sterility: Bags have the potential to leak. - Nov 18, 2016 · Class II · Cantrell Drug Company · 2 recall notices
Lack of Assurance of Sterility - the firm is recalling select sterile drug products. - Aug 21, 2015 · Class II · Cantrell Drug Company
Stability Data Does Not Support Expiry - Jun 3, 2015 · Class II · Baxter Healthcare Corp
Subpotent Drug; out of specification results for heparin raw material - Oct 30, 2014 · Class II · Baxter Healthcare Corp.
Subpotent Drug: Heparin raw material was found to have low potency - Sep 11, 2014 · Class I · Hospira Inc.
Presence of Particulate Matter: A particulate, confirmed as human hair, was found sealed between the tube and film at the round seal of the unused administrative port of the container. - Jun 6, 2014 · Class II · Hospira Inc.
Lack of Assurance of Sterility: Confirmed consumer report of fluid leaking from primary container of bag. - Jan 22, 2014 · Class II · Fresenius Kabi USA, LLC
Subpotent; 18 month time point - Jan 9, 2014 · Class II · Hospira Inc.
Lack of Assurance of Sterility; potential leakage from administrative port.
Class I recalls are the most serious; Class III the least. A recall covers specific lots, listed on each recall.