Biguanide, Sodium-Glucose Cotransporter 2 Inhibitor
Where is Canagliflozin and Metformin made?
1 company sell it under their own name. Their labels name 8 factories in Belgium, Spain, the United States, India and Italy.
Belgium 2Spain 2United States 2India 1Italy 1
Companies and their factories
| Company on the label | Factory | Where | Last FDA inspection |
|---|---|---|---|
| Janssen Pharmaceuticals, Inc. Invokamet, Invokamet XR50 mg / 1000 mg, 50 mg / 500 mg, 150 mg / 1000 mg, 150 mg / 500 mg · NDC 50458-543, 50458-943, 50458-542 +5 | Ajinomoto OmnichemMakes the active ingredient | Wetteren, Belgium | Problems found, fixed voluntarilyJun 2025 |
| Farmhispania S.A.Makes the active ingredient and tests it | Montmelo, Spain | Problems found, fixed voluntarilyMay 2023 | |
| Granules India LimitedMakes the active ingredient and tests it | Medchal-Malkajgiri District, India | No problems foundJun 2023 | |
| Janssen Cilag SpAMakes it and packages it | Borgo San Michele, Italy | Problems found, fixed voluntarilySep 2024 | |
| Janssen Ortho LLCMakes it, tests it, packages it and labels it | Gurabo, PR, United States | Problems found, fixed voluntarilyMar 2023 | |
| Janssen Pharmaceutica NVMakes the active ingredient and tests it | Geel, Belgium | Problems found, fixed voluntarilyMar 2024 | |
| Patheon Puerto Rico, Inc.Makes it | Manati, PR, United States | Problems found, fixed voluntarilyJul 2022 | |
| Rolabo Outsourcing S.L.Makes the active ingredient | Zaragoza, Spain | Problems found, fixed voluntarilyDec 2023 |
Recalls
- Oct 19, 2016 · Class III · Janssen Ortho L.L.C.
Labeling: Incorrect or Missing Package Insert - Xarelto prescribing information outserts may be affixed to the exterior of Invokamet bottles in place of the Invokamet prescribing information outsert.
Class I recalls are the most serious; Class III the least. A recall covers specific lots, listed on each recall.