alpha-Adrenergic Agonist, beta-Adrenergic Blocker
Where is Brimonidine and Timolol made?
16 companies sell it under their own name and 1 repackager rebottle it. Their labels name 9 factories in India, Switzerland, Turkey, South Korea and Greece.
India 5Switzerland 1Turkey 1South Korea 1Greece 1
Companies and their factories
| Company on the label | Factory | Where | Last FDA inspection |
|---|---|---|---|
| Alembic Pharmaceuticals Inc.2 mg per 1 mL / 5 mg per 1 mL · NDC 62332-706 | Alembic Pharmaceuticals LimitedMakes it | Vadodara, India | Problems found, fixed voluntarilyFeb 2026 |
| Alembic Pharmaceuticals Limited2 mg per 1 mL / 5 mg per 1 mL · NDC 46708-706 | Alembic Pharmaceuticals LimitedMakes it | Vadodara, India | Problems found, fixed voluntarilyFeb 2026 |
| Armas Pharmaceuticals Inc.2 mg per 1 mL / 5 mg per 1 mL · NDC 72485-634 | Ophtapharm AGMakes it, packages it and labels it | Hettlingen, Switzerland | Problems found, fixed voluntarilyFeb 2020 |
| Caplin Steriles Limited2 mg per 1 mL / 5 mg per 1 mL · NDC 65145-162, 65145-163, 65145-164 | Caplin Steriles LimitedMakes it, tests it and packages it | Gummidipoondi, India | No problems foundAug 2024 |
| Devatis, Inc.2 mg per 1 mL / 5 mg per 1 mL · NDC 73043-029 | Deva Holding A S-Kartepe Uretim TesisleriMakes it | Kocaeli, Turkey | No problems foundDec 2023 |
| Florida Pharmaceutical Products, LLC.2 mg per 1 mL / 5 mg per 1 mL · NDC 71921-188 | Indoco Remedies LimitedMakes it, tests it, packages it and labels it | Goa, India | Serious problems, FDA actionFeb 2023 |
| Gland Pharma Limited2 mg per 1 mL / 5 mg per 1 mL · NDC 68083-624, 68083-625, 68083-664 | Gland Pharma LimitedMakes it, tests it, packages it and labels it | Hyderabad, India | Problems found, fixed voluntarilyJul 2024 |
| Glenmark Pharmaceuticals Inc., USA2 mg per 1 mL / 5 mg per 1 mL · NDC 68462-281 | Sam Chun Dang Pharm Co, LtdMakes it | Hwaseong, South Korea | Serious problems, FDA actionMay 2026 |
| Leading Pharma, LLC2 mg per 1 mL / 5 mg per 1 mL · NDC 69315-330 | Caplin Steriles LimitedMakes it, tests it and packages it | Gummidipoondi, India | No problems foundAug 2024 |
| Northstar Rx LLC.2 mg per 1 mL / 5 mg per 1 mL · NDC 72603-931 | Indoco Remedies LimitedMakes it, tests it, packages it and labels it | Goa, India | Serious problems, FDA actionFeb 2023 |
| Somerset Therapeutics, LLC2 mg per 1 mL / 5 mg per 1 mL · NDC 70069-651, 70069-652, 70069-653 | Somerset Therapeutics Private LimitedMakes it, tests it, packages it and labels it | Bengaluru, India | Serious problems, FDA actionFeb 2025 |
| Upsher-Smith Laboratories, Inc.2 mg per 1 mL / 5 mg per 1 mL · NDC 0832-1425 | Rafarm S.A.Makes it | Paiania, Greece | Problems found, fixed voluntarilyJun 2024 |
| Allergan, Inc. Combigan2 mg per 1 mL / 5 mg per 1 mL · NDC 0023-9211 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Apotex Corp.2 mg per 1 mL / 5 mg per 1 mL · NDC 60505-0589 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Pacific Pharma, Inc.2 mg per 1 mL / 5 mg per 1 mL · NDC 82182-455 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Sandoz Inc.2 mg per 1 mL / 5 mg per 1 mL · NDC 0781-7186 | The label doesn't name the factory. Plants this company names for other drugs | ||
Repackaged by
These companies buy Brimonidine and Timolol in bulk and rebottle it, often for mail-order, clinic or hospital pharmacies. If your bottle shows one of these names, open its NDC to see who made the pills inside.
- Physicians Total Care, Inc.:
54868-6295
Recalls
- Mar 5, 2026 · Class II · Apotex Corp.
Lack of Assurance of Sterility - Sep 5, 2025 · Class II · Apotex Corp.
Lack of Assurance of Sterility; atypical weight loss due to improper bottle sealing leading to potential sterility concerns - May 28, 2025 · Class II · Apotex Corp.
Lack of Assurance of Sterility - Mar 19, 2019 · Class II · Allergan Sales, LLC
cGMP Deviations - Oct 19, 2017 · Class III · Allergan Sales, LLC
Failed Impurities/Degradation Specifications.
Class I recalls are the most serious; Class III the least. A recall covers specific lots, listed on each recall.