Central alpha-2 Adrenergic Agonist
Where is Tizanidine made?
25 companies sell it under their own name and 38 repackagers rebottle it. Their labels name 14 factories in India, the United States, China and Hungary.
India 10United States 2China 1Hungary 1
Companies and their factories
| Company on the label | Factory | Where | Last FDA inspection |
|---|---|---|---|
| Aurobindo Pharma Limited2 mg, 4 mg, 6 mg · NDC 59651-314, 84386-023, 59651-315 +2 | Apl Healthcare LimitedMakes it and tests it | Tirupati, India | Problems found, fixed voluntarilyDec 2025 |
| Aurovitas Pharma Taizhou Co.,LTDMakes it and tests it | Taizhou, China | Not inspected on record | |
| Dr.Reddy's Laboratories Ltd.2 mg, 4 mg · NDC 55111-179, 55111-180 | Dr. Reddy's Laboratories LimitedMakes it and tests it | Medchal-Malkajgiri, India | Problems found, fixed voluntarilyOct 2023 |
| Dr. Reddy's Laboratories LimitedMakes it and tests it | Srikakulam, India | Problems found, fixed voluntarilyMay 2022 | |
| Advagen Pharma Ltd.2 mg, 4 mg, 6 mg, 8 mg · NDC 72888-001, 72888-002, 72888-003 +1 | Rubicon Research LimitedMakes it, tests it, packages it and labels it | Thane, India | No problems foundMar 2024 |
| Alembic Pharmaceuticals Inc.2 mg, 4 mg, 6 mg · NDC 62332-491, 62332-492, 62332-493 | Alembic Pharmaceuticals LimitedMakes it | Panchmahal, India | No problems foundJul 2024 |
| Alembic Pharmaceuticals Limited2 mg, 4 mg, 6 mg · NDC 46708-491, 46708-492, 46708-493 | Alembic Pharmaceuticals LimitedMakes it | Panchmahal, India | No problems foundJul 2024 |
| Ascend Laboratories, LLC2 mg, 4 mg, 6 mg · NDC 67877-613, 67877-610, 67877-614 +2 | Alkem Laboratories LimitedMakes it, tests it and packages it | Amaliya Daman, India | No problems foundAug 2019 |
| Cadila Healthcare Limited2 mg, 4 mg, 6 mg · NDC 70771-1335, 70771-1067, 70771-1336 +2 | Zydus Lifesciences LimitedMakes it and tests it | Ahmedabad, India | Problems found, fixed voluntarilyMar 2023 |
| Cadila Pharmaceuticals Limited2 mg, 4 mg, 6 mg · NDC 71209-064, 71209-065, 71209-066 | Cadila Pharmaceuticals LimitedMakes it, tests it, packages it and labels it | Ahmedabad, India | No problems foundSep 2025 |
| Caraco Pharmaceutical Laboratories, Ltd.2 mg, 4 mg · NDC 57664-502, 57664-503 | ALKALOIDA Vegyeszeti Gyar zartkoruen mukodo ReszvenytarsasagMakes it, tests it and packages it | Tiszavasvari, Hungary | Problems found, fixed voluntarilyMar 2025 |
| Covis Pharma US, Inc Zanaflex2 mg, 4 mg, 6 mg · NDC 70515-602, 70515-604, 70515-594 +1 | Patheon Manufacturing Services LLCMakes it | Greenville, NC, United States | No problems foundSep 2025 |
| Ingenus Pharmaceuticals, LLC2 mg, 4 mg, 6 mg · NDC 50742-224, 50742-225, 50742-226 | Stallion Laboratories Private LimitedMakes it, tests it and packages it | Ahmedabad, India | Problems found, fixed voluntarilyJul 2024 |
| Kanchan Healthcare Inc2 mg, 4 mg, 6 mg · NDC 85742-031, 85742-032, 85742-033 | Cadila Pharmaceuticals LimitedMakes it, tests it, packages it and labels it | Ahmedabad, India | No problems foundSep 2025 |
| Modavar Pharmaceuticals LLC2 mg, 4 mg, 6 mg · NDC 72241-041, 72241-042, 72241-043 | Cadila Pharmaceuticals LimitedMakes it, tests it, packages it and labels it | Ahmedabad, India | No problems foundSep 2025 |
| New Horizon Rx Group, LLC4 mg · NDC 58517-380 | Caraco Pharmaceutical Laboratories, Ltd.Makes it | Farmington Hills, Michigan, United States | Problems found, fixed voluntarilyDec 2008 |
| Northstar Rx LLC.2 mg, 4 mg · NDC 16714-171, 16714-172 | Dr. Reddy's Laboratories LimitedMakes it and tests it | Srikakulam, India | Problems found, fixed voluntarilyMay 2022 |
| Rising Pharma Holdings, Inc.2 mg, 4 mg · NDC 64980-658, 64980-659 | Graviti Pharmaceuticals Private LimitedMakes it and tests it | Sangareddy, India | Problems found, fixed voluntarilyJul 2026 |
| Viona Pharmaceuticals Inc.2 mg, 4 mg · NDC 72578-096, 72578-097 | Zydus Lifesciences LimitedMakes it and tests it | Ahmedabad, India | Problems found, fixed voluntarilyMar 2023 |
| Zydus Pharmaceuticals (USA) Inc.2 mg, 4 mg, 6 mg · NDC 70710-1111, 70710-1112, 70710-1113 | Zydus Lifesciences LimitedMakes it and tests it | Ahmedabad, India | Problems found, fixed voluntarilyMar 2023 |
| Actavis Pharma, Inc.2 mg, 4 mg, 6 mg · NDC 0591-2788, 0591-2789, 0591-2790 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Apotex Corp.2 mg, 4 mg, 6 mg · NDC 60505-0251, 60505-2648, 60505-0252 +2 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Legacy Pharma USA, Inc. Zanaflex2 mg, 4 mg, 6 mg · NDC 83107-001, 83107-002, 83107-004 +1 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Medcore LLC2 mg, 4 mg · NDC 82461-720, 82461-721 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Rosemont Pharmaceuticals, LLC Ontralfy2 mg per 5 mL · NDC 69528-310 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Trifluent Pharma, Inc.8 mg · NDC 73352-090, 73352-089 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Unichem Pharmaceuticals (USA), Inc.2 mg, 4 mg · NDC 29300-168, 29300-169 | The label doesn't name the factory. Plants this company names for other drugs | ||
Repackaged by
These companies buy Tizanidine in bulk and rebottle it, often for mail-order, clinic or hospital pharmacies. If your bottle shows one of these names, open its NDC to see who made the pills inside.
- A-S Medication Solutions:
50090-2078,50090-7716,50090-0811,50090-2208+5 - Advanced Rx Pharmacy of Tennessee, LLC:
80425-0187,80425-0436,80425-0500,80425-0425+9 - Aidarex Pharmaceuticals LLC:
33261-103,53217-344,33261-104,53217-211 - Altura Pharmaceuticals, Inc.:
63874-087 - American Health Packaging:
68084-775,68084-645 - Aphena Pharma Solutions - Tennessee, Inc.:
71610-345,71610-455,71610-228,71610-355+2 - Asclemed USA, Inc.:
76420-865,76420-885,76420-338,76420-228+8 - AvKARE, Inc.:
42291-810,42291-811,42291-812 - AvPAK:
50268-759,50268-760 - Blenheim Pharmacal, Inc.:
10544-587,10544-863,10544-576,10544-890 - Bryant Ranch Prepack:
63629-3209,72162-1641,63629-8533,63629-8871+24 - Cardinal Health 107, LLC:
55154-7287 - Central Packaging:
80175-0169 - Coupler LLC:
67046-1444 - Denton Pharma, Inc. DBA Northwind Pharmaceuticals.:
70934-811 - Direct Rx:
61919-220,61919-811,72189-599,61919-221+4 - Dispensing Solutions Inc.:
66336-843 - H.J. Harkins Co., Inc.:
52959-691,52959-689 - Hawaii Repack, Inc.:
85534-0029,85534-0030 - Keltman Pharmaceuticals Inc.:
68387-130,68387-140 - Lake Erie Medical DBA Quality Care Products LLC:
35356-662,49999-347 - Major Pharmaceuticals:
0904-6418 - Medsource Pharmaceuticals:
45865-386,45865-348,45865-954 - NCS HealthCare of KY, Inc dba Vangard Labs:
0615-8468,0615-8469 - Northwind Pharmaceuticals:
51655-740,51655-603 - NuCare Pharmaceuticals.Inc.:
68071-3440,68071-5268,68071-3719,68071-4463 - PD-Rx Pharmaceuticals, Inc.:
72789-326,43063-868,72789-506,72789-327+4 - Phoenix RX LLC:
85509-1180 - Physicians Total Care, Inc.:
54868-4964,54868-4939 - Preferred Pharmaceuticals, Inc..:
68788-7991,68788-8802,68788-8776,68788-8798+5 - Proficient Rx LP:
71205-311,63187-910,63187-673,63187-145+2 - RPK Pharmaceuticals, Inc.:
53002-1418,53002-1437 - Rebel Distributors Corp..:
21695-126,21695-127,21695-373 - RedPharm Drug. Inc.:
67296-2209,67296-2316,67296-1567,67296-1417+5 - Remedyrepack Inc.:
70518-3112,70518-3181,70518-0133,70518-1598+3 - St. Mary's Medical Park Pharmacy:
60760-694,60760-505,60760-892 - Stat Rx USA:
42549-549,16590-220,16590-871,42549-597+2 - Unit Dose Services:
50436-6755,50436-0251,50436-6756,50436-0252+1
Recalls
- Jan 2, 2024 · Class II · Dr. Reddy's Laboratories, Inc.
Presence of Foreign tablets/capsules - identified as tizanidine 2 mg tablets. - Jun 26, 2023 · Class II · Preferred Pharmaceuticals, Inc.
Failed Stability Specifications - Jun 23, 2023 · Class II · Amerisource Health Services LLC
Failed Dissolution Specifications: this repackaged product was recalled by the manufacturer, Dr. Reddy's Laboratories, Inc., due to out of specification results for dissolution. - Jun 21, 2023 · Class II · Dr Reddy's Laboratories Limited
Failed dissolution specification: Out of specification results observed in 24-month long term stability testing. - Jul 19, 2021 · Class II · Dr. Reddy's Laboratories, Inc.
Failed Tablet/Capsule Specification: Some tablets are shaved - Nov 24, 2020 · Class II · Ascend Laboratories LLC
Failed Dissolution Specifications; Out of Specification (low) results were obtained. - Sep 4, 2018 · Class II · Dr. Reddy's Laboratories, Inc.
Presence of Foreign Tablets/Capsules: Glimepiride tablet was found in a bottle of Tinzadine Hcl Tablets . - Mar 19, 2013 · Class III · Dr. Reddy'S Laboratories
Labeling Illegible: There is a possibility that the bottle labels do not contain the strength of the product as well as other printing details. - Jul 23, 2012 · Class III · Stat Rx USA
Labeling: Label Mix-Up; Some bottles of Tizanidine 4mg Tablets, had the incorrect manufacturer (Actavis) printed on the label.
Class I recalls are the most serious; Class III the least. A recall covers specific lots, listed on each recall.