Folate Analog Metabolic Inhibitor
Where is Pemetrexed made?
23 companies sell it under their own name. Their labels name 14 factories in India, China and the United States.
India 10China 2United States 2
Companies and their factories
| Company on the label | Factory | Where | Last FDA inspection |
|---|---|---|---|
| BluePoint Laboratories.100 mg per 4 mL, 500 mg per 20 mL, 750 mg per 30 mL, 1000 mg per 40 mL · NDC 68001-538, 68001-535, 68001-543 +6 | EUGIA Pharma Specialities LimitedMakes it and tests it | Medchal-Malkajgiri, India | No problems foundJul 2023 |
| Gland Pharma LimitedMakes it and tests it | Visakhapatnam, India | No problems foundJul 2023 | |
| Qilu Pharmaceutical (Hainan) Co., Ltd.Makes it and tests it | Haikou, China | Problems found, fixed voluntarilyMay 2023 | |
| Biocon Pharma Inc.1000 mg per 40 mL · NDC 70377-022 | MSN Laboratories Private LimitedMakes it | Rangareddy District, India | Problems found, fixed voluntarilyDec 2023 |
| Shilpa Pharma Lifesciences LimitedMakes the active ingredient | Raichur, India | No problems foundMar 2025 | |
| Fresenius Kabi, LLC1 g per 40 mL, 100 mg per 4 mL, 500 mg per 20 mL, 750 mg per 30 mL · NDC 63323-622, 63323-134, 63323-450 +1 | Fresenius Kabi USA, LLCMakes it and tests it | Grand Island, NY, United States | Problems found, fixed voluntarilyOct 2023 |
| Fresenius Kabi USA, LLCMakes it and tests it | Melrose Park, IL, United States | Problems found, fixed voluntarilyAug 2023 | |
| Accord Healthcare Inc.1 g per 40 mL, 100 mg per 4 mL, 500 mg per 20 mL · NDC 16729-244, 16729-229, 16729-230 | Intas Pharmaceuticals LimitedMakes it and tests it | Ahmedabad, India | Serious problems, FDA actionDec 2022 |
| Amneal Pharmaceuticals LLC Pemrydi Rtu100 mg per 10 mL, 500 mg per 50 mL, 1000 mg per 100 mL · NDC 70121-2453, 70121-2462, 70121-2461 | Zydus Lifesciences LimitedMakes it and tests it | Ahmedabad, India | Problems found, fixed voluntarilyJun 2025 |
| AuroMedics Pharma LLC100 mg per 4 mL, 500 mg per 20 mL, 1000 mg per 40 mL · NDC 55150-381, 55150-383, 55150-382 | EUGIA Pharma Specialities LimitedMakes it, tests it and packages it | Medchal-Malkajgiri, India | No problems foundJul 2023 |
| Avyxa Pharma, LLC Pemetrexed Dipotassium, Axtle100 mg per 4 mL, 500 mg per 20 mL · NDC 83831-111, 83831-131, 83831-112 +1 | Gland Pharma LimitedMakes it, makes the active ingredient, tests it, packages it and labels it | Visakhapatnam, India | No problems foundJul 2023 |
| Camber Pharmaceuticals Inc.100 mg per 4 mL, 500 mg per 20 mL · NDC 31722-336, 31722-337 | Hetero Labs LimitedMakes it | Mahabubnagar, India | Problems found, fixed voluntarilyJun 2026 |
| Dr. Reddy's Laboratories Inc.1 g per 40 mL, 100 mg per 4 mL, 500 mg per 20 mL · NDC 43598-370, 43598-386, 43598-387 | Dr.reddy's Laboratories LimitedMakes it and tests it | Visakhapatnam, India | Problems found, fixed voluntarilyMay 2024 |
| Hospira, Inc.1 g per 40 mL, 100 mg per 4 mL, 500 mg per 20 mL · NDC 0409-3532, 0409-0004, 0409-1045 +3 | Zydus Hospira Oncology Private LimitedMakes it, tests it, packages it and labels it | Ahmedabad, India | Problems found, fixed voluntarilyJun 2023 |
| Qilu Pharmaceutical Co., Ltd.100 mg per 4 mL, 500 mg per 20 mL · NDC 67184-0503, 67184-0504 | Qilu Pharmaceutical (Hainan) Co., Ltd.Makes it, tests it, packages it and labels it | Haikou, China | Problems found, fixed voluntarilyMay 2023 |
| Shilpa Medicare Limited100 mg per 10 mL, 500 mg per 50 mL, 1000 mg per 100 mL · NDC 63759-3048, 63759-3050, 63759-3049 | Zydus Lifesciences LimitedMakes it and tests it | Ahmedabad, India | Problems found, fixed voluntarilyJun 2025 |
| Solco Healthcare U.S., LLC100 mg · NDC 43547-632 | Zhejiang Huahai Pharmaceutical Co., Ltd.Makes it | Linhai, China | Serious problems, FDA actionApr 2026 |
| Somerset Therapeutics, LLC100 mg per 4 mL, 500 mg per 20 mL · NDC 70069-834, 70069-835 | Reliance Life Sciences Private LimitedMakes it, makes the active ingredient, tests it, packages it and labels it | Navi Mumbai, India | Serious problems, FDA actionFeb 2026 |
| Waverley Pharma Inc100 mg per 4 mL, 500 mg per 20 mL · NDC 72338-100, 72338-101 | Reliance Life Sciences Private LimitedMakes it, makes the active ingredient and packages it | Navi Mumbai, India | Serious problems, FDA actionFeb 2026 |
| Acacia Pharma, Ltd. Pemfexy25 mg per 1 mL · NDC 71390-250 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Eagle Pharmaceuticals, Inc. Pemfexy25 mg per 1 mL · NDC 42367-531 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Eli Lilly and Company Alimta100 mg per 4 mL, 500 mg per 20 mL · NDC 0002-7640, 0002-7623 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Meitheal Pharmaceuticals Inc.1 g per 40 mL, 100 mg per 10 mL, 100 mg per 4.2 mL, 500 mg per 20 mL, 500 mg per 50 mL, 750 mg per 30 mL · NDC 71288-148, 71288-166, 71288-145 +3 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Northstar Rx LLC.100 mg per 10 mL, 500 mg per 50 mL · NDC 72603-325, 72603-425 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Sagent Pharmaceuticals100 mg per 4.2 mL, 500 mg per 20 mL · NDC 25021-260, 25021-261 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Sandoz Inc.100 mg per 4 mL, 500 mg per 20 mL, 1000 mg per 40 mL · NDC 0781-3518, 0781-3520, 0781-3519 | The label doesn't name the factory. Plants this company names for other drugs | ||
| Teva Pharmaceuticals, Inc.25 mg per 1 mL · NDC 0480-4516, 0480-4514, 0480-4515 | The label doesn't name the factory. Plants this company names for other drugs | ||
Recalls
- Jul 29, 2026 · Class II · Shilpa Medicare Limited · 2 recall notices
Discolored solution. The firm has received market complaints reporting green to dark green discoloration in certain vials
Class I recalls are the most serious; Class III the least. A recall covers specific lots, listed on each recall.